Six series of novel isosteviol derivatives; modified in the C-19 position; were synthesized; and their antiproliferative activity was evaluated against three human cancer cell lines (HCT-116; BEL-7402; HepG2) and the human L02 normal cell line in vitro.Most of the derivatives tested here exhibited improved antiproliferative activity with high selec
Groundwater is one of the most essential natural resources and is affected by climate variability.However, our understanding of the effects of climate on groundwater recharge (R), particularly in dry regions, is limited.Future climate projections suggest changes in many statistical characteristics of the potential evapotranspiration (Ep) and the ra
Abstract The acquisition of basic surgical skills is a key component of medical education and trainees in laparoscopic surgery typically begin developing their skills using simulation box trainers.However, despite the advantages of simulation surgical training, access can be difficult for many trainees.One technique that has shown promise to enhanc
The aim of this study is to examine the effect of Participative Budgeting on Budgetary Slack with Organizational Politics as a moderating variable in the public sector; examine the effect of Budgetary Slack on Performance Based Budgeting.This study examines data using a causal model with Partial Least Square (PLS) statistical analysis tools.The dat